BDBM50188689 (R)-tert-butyl 2-(4-(3-Chloro-5-(hydroxymethyl)pyridin-2-yl)-2-methylpiperazin-1-yl)-6-(trifluoromethyl)-1H-benzo[d]imidazol-4-ylcarbamate::CHEMBL208777

SMILES C[C@@H]1CN(CCN1c1nc2cc(cc(NC(=O)OC(C)(C)C)c2[nH]1)C(F)(F)F)c1ncc(CO)cc1Cl

InChI Key InChIKey=SPIMJNQRNKJTCD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188689   

LigandPNGBDBM50188689((R)-tert-butyl 2-(4-(3-Chloro-5-(hydroxymethyl)pyr...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity against acid-induced 45calcium ion uptake in CHO cells expressing rat TRPV1 at pH5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50188689((R)-tert-butyl 2-(4-(3-Chloro-5-(hydroxymethyl)pyr...)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity against capsaicin-induced 45calcium ion uptake in CHO cells expressing rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed