BDBM50188883 CHEMBL378285::rac-8-(1-phenyl-cyclohexyl)-4-p-tolyl-2,8-diaza-spiro[4.5]decan-1-one

SMILES Cc1ccc(cc1)C1CNC(=O)C11CCN(CC1)C1(CCCCC1)c1ccccc1

InChI Key InChIKey=OALSVDCRGQVHMD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188883   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188883(rac-8-(1-phenyl-cyclohexyl)-4-p-tolyl-2,8-diaza-sp...)
Affinity DataEC50:  139nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed