BDBM50189081 6-butyl-9a-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one::CHEMBL213051

SMILES CCCCC1=C2c3ccc4nn[nH]c4c3CC2(CC)CCC1=O

InChI Key InChIKey=QUCNJOJHJPTUQH-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189081   

TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189081(6-butyl-9a-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-tri...)
Affinity DataIC50: 43nMAssay Description:Binding affinity to human recombinant ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189081(6-butyl-9a-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-tri...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human recombinant ERbeta expressed in HEK293 cells by alkaline phosphatase reporter gene transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189081(6-butyl-9a-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-tri...)
Affinity DataEC50:  681nMAssay Description:Agonist activity at human recombinant ERalpha expressed in HEK293 cells by alkaline phosphatase reporter gene transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189081(6-butyl-9a-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-tri...)
Affinity DataIC50: 1.13E+3nMAssay Description:Binding affinity to human recombinant ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed