BDBM50189086 9a-butyl-6-methyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one::CHEMBL377457

SMILES CCCCC12Cc3c(ccc4nn[nH]c34)C1=C(C)C(=O)CC2

InChI Key InChIKey=VOKUMQGNXZJKDV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189086   

TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189086(9a-butyl-6-methyl-8,9,9a,10-tetrahydro-3H-1,2,3-tr...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human recombinant ERbeta expressed in HEK293 cells by alkaline phosphatase reporter gene transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189086(9a-butyl-6-methyl-8,9,9a,10-tetrahydro-3H-1,2,3-tr...)
Affinity DataIC50: 27nMAssay Description:Binding affinity to human recombinant ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189086(9a-butyl-6-methyl-8,9,9a,10-tetrahydro-3H-1,2,3-tr...)
Affinity DataIC50: 5.98E+3nMAssay Description:Binding affinity to human recombinant ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed