BDBM50189314 CHEMBL3827058

SMILES COc1ccc(cc1)-c1cc2cc(OCCCN(C)Cc3cccc(OC(=O)NCCCCCc4ccccc4)c3)ccc2oc1=O

InChI Key InChIKey=AKOGQQINMRSZAR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189314   

TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50189314(CHEMBL3827058)
Affinity DataIC50:  179nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 120 mins followed by subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50189314(CHEMBL3827058)
Affinity DataIC50:  211nMAssay Description:Inhibition of FAAH in rat brain membrane using N-arachidonoyl-[14C]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50189314(CHEMBL3827058)
Affinity DataIC50:  2.83E+3nMAssay Description:Inhibition of FAAH in rat brain membrane using N-arachidonoyl-[14C]-ethanolamine as substrate incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50189314(CHEMBL3827058)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed