BDBM50189502 CHEMBL3827832

SMILES CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1

InChI Key InChIKey=PFSWASUQURIOOR-UHFFFAOYSA-N

Data  1 KI  13 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50189502   

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataKi:  0.626nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  653nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  512nMAssay Description:Agonist activity at human GPR84 fused with bovine Galphai1 protein expressed in baculovirus infected sf9 cell membrane incubated for 1 hr by [35S]GTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  512nMAssay Description:Agonist activity at human GPR84 by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  512nMAssay Description:Agonist activity at human Gi1alpha-coupled GPR84 expressed in baculovirus infected Sf9 insect cells assessed as stimulation of [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  114nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cells assessed as beta-arrestin 2 recruitment measured after 90 mins by beta-galactosida...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  1.10E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO-K1 cells assessed as induction of beta-arrestin recruitment by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  341nMAssay Description:Agonist activity at recombinant human GPR84 stably expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of forskolin-induced cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  1.25E+3nMAssay Description:Agonist activity at recombinant human GPR84 stably expressed in HEK293 cells co-expressing Galpha16 assessed as increase in intracellular calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  1.75E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in HEK293 cells assessed as beta-arrestin 2 recruitment measured after 20 mins by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  17nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cells co-expressing beta-galactosidase/beta-arrestin2 assessed as inhibition of forskoli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human GPR84 expressed in CHO-K1 cells assessed as reduction in forskolin-stimulated cAMP production incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  653nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataEC50:  105nMAssay Description:Agonist activity at recombinant human GPR84 expressed in HEK293 cells co-expressing Gqi5 assessed as increase in myo-[3H]inositol phosphate accumulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed