BDBM50189575 CHEMBL3827335

SMILES COC(=O)N(CC(O)=O)Cc1cc(F)cc(OCc2nc(oc2C)-c2ccc(Cl)cc2)c1

InChI Key InChIKey=WRIGKAXYBAIJRE-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189575   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50189575(CHEMBL3827335)
Affinity DataEC50:  18nMAssay Description:Agonist activity at Gal4-tagged human PPAR-alpha expressed in HEK cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50189575(CHEMBL3827335)
Affinity DataEC50:  2.82E+3nMAssay Description:Agonist activity at Gal4-tagged human PPAR-gamma expressed in HEK cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50189575(CHEMBL3827335)
Affinity DataIC50:  1.34E+3nMAssay Description:Binding affinity to human GST-tagged PPAR-alpha LBD expressed in Escherichia coli BL21 (DE3) PlysS after 30 mins in presence of fluorescein ligand FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50189575(CHEMBL3827335)
Affinity DataIC50: >1.50E+4nMAssay Description:Binding affinity to human GST-tagged PPAR-gamma LBD expressed in Escherichia coli BL21 after 30 mins in presence of fluorescein ligand FLA-A by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed