BDBM50190059 CHEMBL425069::N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-2,6-dimethoxy-benzamide

SMILES COc1cccc(OC)c1C(=O)NN1c2ccc(Cl)cc2N=C(N2CCN(C)CC2)c2ccccc12

InChI Key InChIKey=ADLYXAHODXNVQT-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50190059   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190059(CHEMBL425069 | N-[8-chloro-11-(4-methyl-piperazin-...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190059(CHEMBL425069 | N-[8-chloro-11-(4-methyl-piperazin-...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190059(CHEMBL425069 | N-[8-chloro-11-(4-methyl-piperazin-...)
Affinity DataKi:  13.8nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190059(CHEMBL425069 | N-[8-chloro-11-(4-methyl-piperazin-...)
Affinity DataKi:  38nMAssay Description:Binding affinity at dopamine D5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190059(CHEMBL425069 | N-[8-chloro-11-(4-methyl-piperazin-...)
Affinity DataKi:  169nMAssay Description:Binding affinity at adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190059(CHEMBL425069 | N-[8-chloro-11-(4-methyl-piperazin-...)
Affinity DataKi:  340nMAssay Description:Binding affinity at dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190059(CHEMBL425069 | N-[8-chloro-11-(4-methyl-piperazin-...)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]methylspiperone from dopamine D2 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190059(CHEMBL425069 | N-[8-chloro-11-(4-methyl-piperazin-...)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]methylspiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190059(CHEMBL425069 | N-[8-chloro-11-(4-methyl-piperazin-...)
Affinity DataKi:  1.81E+3nMAssay Description:Binding affinity at dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed