BDBM50190193 CHEMBL213834::naphthalene-1-carboxylic acid [8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-amide

SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc3ccccc23)c2ccccc12

InChI Key InChIKey=VTTMDSGFQMHASZ-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50190193   

Target5-hydroxytryptamine receptor 2A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190193(naphthalene-1-carboxylic acid [8-chloro-11-(4-meth...)
Affinity DataKi:  1nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190193(naphthalene-1-carboxylic acid [8-chloro-11-(4-meth...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190193(naphthalene-1-carboxylic acid [8-chloro-11-(4-meth...)
Affinity DataKi:  105nMAssay Description:Binding affinity at dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190193(naphthalene-1-carboxylic acid [8-chloro-11-(4-meth...)
Affinity DataKi:  458nMAssay Description:Displacement of [3H]methylspiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190193(naphthalene-1-carboxylic acid [8-chloro-11-(4-meth...)
Affinity DataKi:  458nMAssay Description:Binding affinity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190193(naphthalene-1-carboxylic acid [8-chloro-11-(4-meth...)
Affinity DataKi:  882nMAssay Description:Binding affinity at adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190193(naphthalene-1-carboxylic acid [8-chloro-11-(4-meth...)
Affinity DataKi:  977nMAssay Description:Binding affinity at dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed