BDBM50190290 4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)-1-{(R)-3-[3-(4-chloro-phenyl)-3-methyl-butylamino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-methyl-amide::CHEMBL382851

SMILES CN([C@H]1CCN(C1)C(=O)N1CC[C@H](C1)NCCC(C)(C)c1ccc(Cl)cc1)C(=O)c1ccc(cc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ZIYMZLIFVYQZGG-JSOSNVBQSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190290   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190290(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190290(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190290(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of HERG potassium channel expressed in HEK cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed