BDBM50190367 1-{3-[3-(tert-butyl) phenyl]-(1,2,4-triazol-4-yl) }-3-phenol::CHEMBL377340

SMILES CC(C)(C)c1cccc(c1)-c1nncn1-c1cccc(O)c1

InChI Key InChIKey=ADWNAWYRPYHKKB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190367   

TargetDelta-type opioid receptor(Human)
University of Medicine and Dentistry of New Jersey and Umdnj Informatics Institute

Curated by ChEMBL
LigandPNGBDBM50190367(1-{3-[3-(tert-butyl) phenyl]-(1,2,4-triazol-4-yl) ...)
Affinity DataKi:  230nMAssay Description:Inhibition of (-)-[9-3H]bremazocine binding to delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Medicine and Dentistry of New Jersey and Umdnj Informatics Institute

Curated by ChEMBL
LigandPNGBDBM50190367(1-{3-[3-(tert-butyl) phenyl]-(1,2,4-triazol-4-yl) ...)
Affinity DataKi:  850nMAssay Description:Inhibition of (-)-[9-3H]bremazocine binding to mu opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Medicine and Dentistry of New Jersey and Umdnj Informatics Institute

Curated by ChEMBL
LigandPNGBDBM50190367(1-{3-[3-(tert-butyl) phenyl]-(1,2,4-triazol-4-yl) ...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of (-)-[9-3H]bremazocine binding to kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed