BDBM50190549 1-[4-hydroxy-3-(tritylaminomethyl)butyl]uracil::CHEMBL378101

SMILES O=c1ccn(CCC(CO)CNC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1

InChI Key InChIKey=AROLDFLIRWDCKX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190549   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum (isolate 3D7))
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190549BDBM50190549(1-[4-hydroxy-3-(tritylaminomethyl)butyl]uracil | C...)
Affinity DataKi:  240nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Instituto De Parasitolog£A Y Biomedicina L£Pez-Neyra

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190549BDBM50190549(1-[4-hydroxy-3-(tritylaminomethyl)butyl]uracil | C...)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of human dUTPase using dUTP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Instituto De Parasitolog£A Y Biomedicina L£Pez-Neyra

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190549BDBM50190549(1-[4-hydroxy-3-(tritylaminomethyl)butyl]uracil | C...)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of human recombinant dUTPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed