BDBM50191280 5,21-Dibromo-4-hydroxy-2-oxa-10,14-diaza-tricyclo[16.2.2.1*3,7*]tricosa-1(21),3,5,7(23),18(22),19-hexaene-11,15-dione::5,21-dibromo-4-hydroxy-2-oxa-10,14-diaza-tricyclo[16.2.2.10,0]-tricosa-1(21),3(23),4,6,18(22),19-hexaene-11,15-dione::CHEMBL213853

SMILES Oc1c(Br)cc2CCNC(=O)CCNC(=O)CCc3ccc(Oc1c2)c(Br)c3

InChI Key InChIKey=KAVCIWPHSSAORZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191280   

TargetRyanodine receptor 1(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50191280(5,21-Dibromo-4-hydroxy-2-oxa-10,14-diaza-tricyclo[...)
Affinity DataIC50: 6.00E+3nMAssay Description:Binding affinity to RYR1 channels by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed