BDBM50191420 (2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-ylethyl)oxime::CHEMBL379858

SMILES Oc1[nH]c2c(Br)cccc2c1C1=Nc2ccccc2\C1=N/OCCN1CCNCC1

InChI Key InChIKey=GKPYOIONIPTTMQ-NHFJDJAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191420   

TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191420((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50:  5.20E+3nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50191420((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed