BDBM50191563 (S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(4-hydroxyphenyl)propanamide::CHEMBL377620

SMILES CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N1C[C@H](OCc2ccc3ccccc3c2)C[C@@H]1CCCN=C(N)N

InChI Key InChIKey=YPMWOWLUDWNQOB-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50191563   

TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191563BDBM50191563((S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopr...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191563BDBM50191563((S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopr...)
Affinity DataKi:  21nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191563BDBM50191563((S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopr...)
Affinity DataKi:  42nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191563BDBM50191563((S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopr...)
Affinity DataKi:  85nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191563BDBM50191563((S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopr...)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human MC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191563BDBM50191563((S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopr...)
Affinity DataEC50:  88nMAssay Description:Agonist activity at human MC1R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed