BDBM50191614 3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide::CHEMBL380095::rac-3-{cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide
SMILES NC(=O)c1ccc(F)c2OCC(Cc12)N(CCCc1c[nH]c2ccc(F)cc12)C1CCC1
InChI Key InChIKey=PTXOOZZUDQZJHO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50191614
Affinity DataKi: 3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in Sprague-Dawley rat frontal cortical membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in Sprague-Dawley rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO cells by inhibition of 8-OH-DPAT-induced decrease in forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 202nMAssay Description:Activity at human cloned 5HT1A receptor expressed in CHO cells assessed as blockade of 5-HT-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 25.2nMAssay Description:Inhibition of 5-HT transporter-mediated [3H]5HT uptake in human Jar cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25.2nMAssay Description:Inhibition of [3H]5-HT uptake at human 5-HT transporter expressed in Jar cellsMore data for this Ligand-Target Pair