BDBM50191945 CHEMBL3904768
SMILES Cn1nccc1-c1ccn2c(cnc2c1)C(=O)Nc1cc(ccc1F)C(=O)NCc1ccc(F)c(F)c1
InChI Key InChIKey=AFMNYDOAZIYBKT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50191945
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair