BDBM50192007 CHEMBL3902237

SMILES CCN(CCNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(ccn23)-c2ccnn2C)c1)C(C)(C)C

InChI Key InChIKey=LIQIINYHBOBLKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192007   

TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192007(CHEMBL3902237)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192007(CHEMBL3902237)
Affinity DataIC50:  22nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed