BDBM50192018 CHEMBL3350037

SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](CO)[C@@H](C)O)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O

InChI Key InChIKey=DEQANNDTNATYII-JDBXKHNRSA-N

Data  11 KI  2 IC50  6 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50192018   

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi:  0.0530nMAssay Description:Displacement of [125I]-somatostatin from human SSTR2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi:  0.316nMAssay Description:Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi:  0.501nMAssay Description:Binding affinity for SSTR2 receptors of rat cortex membranes was determined by using [125I][Tyr3]-octreotide radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi:  5nMAssay Description:Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi:  5nMAssay Description:Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]-somatostatin from human SSTR5 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]-somatostatin from human SSTR3 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi:  251nMAssay Description:Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi:  300nMAssay Description:Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 4(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]-somatostatin from human SSTR4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 4(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity towards human Somatostatin receptor type 4 (sst4) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKd:  0.610nMAssay Description:Binding affinity to human SST2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKd:  389nMAssay Description:Binding assay at human somatostatin receptor 1 (hsst1) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 4(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKd:  1.74E+3nMAssay Description:Binding assay at human somatostatin receptor 4 (hsst4) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKd:  2.5nMAssay Description:Binding assay at human somatostatin receptor 3 (hsst3) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataIC50:  1nMAssay Description:Binding affinity for SSTR2 receptors of rat cortex membranes was determined by using Y-labelled SMT487 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKd:  0.776nMAssay Description:Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 1/2/3/4/5(Human)
Diatide Research Laboaratories

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKd:  49nMAssay Description:Binding assay at human somatostatin receptor 5 (hsst5) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed