BDBM50192784 (S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-(phenoxymethyl)pyrrolidin-1-ylsulfonyl)indoline-2,3-dione::(S)-1-(4-(2-fluoroethoxy)benzyl)-5-[1-(2-phenoxymethylpyrrolidinyl)sulfonyl]isatin::1-[4-(2-fluoroethoxy)-benzyl]-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione::CHEMBL213759
SMILES FCCOc1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N2CCC[C@H]2COc2ccccc2)cc1
InChI Key InChIKey=JVKBLHAUEXSZHN-NRFANRHFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50192784
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 9.77nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
Affinity DataIC50: 23.5nMAssay Description:Inhibition of human recombinant caspase 7More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant caspase 8More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of caspase 8More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of caspase 3More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of caspase 1More data for this Ligand-Target Pair
TargetCaspase-6(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of caspase 6More data for this Ligand-Target Pair
Affinity DataIC50: 22.4nMAssay Description:Inhibition of caspase 7More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
TargetCaspase-6(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human recombinant caspase 6More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant caspase 8More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human recombinant caspase 3More data for this Ligand-Target Pair
Affinity DataIC50: 23.5nMAssay Description:Inhibition of human recombinant caspase 7More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Inhibition of staurosporine induced activation of caspase 3 activation in human Hela cells assessed as hydrolysis of Z-DEVD-R110 substrate by micropl...More data for this Ligand-Target Pair
TargetCaspase-6(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human recombinant caspase 6More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human recombinant caspase 3More data for this Ligand-Target Pair