BDBM50192793 3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantan-1-yl}-propionic acid::CHEMBL219028

SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@H]1C2C[C@@H]3C[C@H]1C[C@](CCC(O)=O)(C3)C2

InChI Key InChIKey=HHSFEYNQHTXPDX-AHTWWQKHSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50192793   

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192793(3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192793(3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-...)
Affinity DataIC50:  89nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192793(3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-...)
Affinity DataIC50:  89.1nMAssay Description:Inhibition of 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192793(3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-...)
Affinity DataIC50:  455nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192793(3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192793(3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-...)
Affinity DataIC50:  74nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed