BDBM50192806 CHEMBL3960867

SMILES COC(=O)N1CCN(CC1)C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

InChI Key InChIKey=FYQUCEXWWNQYPV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192806   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Shionogi

Curated by ChEMBL

LigandBDBM50192806(CHEMBL3960867)Copy SMILESCopy InChI

Affinity DataIC50:  37nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetTransient receptor potential cation channel subfamily V member 4(Rat)
Shionogi

Curated by ChEMBL

LigandBDBM50192806(CHEMBL3960867)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+3nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL