BDBM50192817 CHEMBL3924485

SMILES COC(=O)N1CC2CCC(C1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

InChI Key InChIKey=WKNDXTPWHMMYGZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192817   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Shionogi

Curated by ChEMBL

LigandBDBM50192817(CHEMBL3924485)Copy SMILESCopy InChI

Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/30/2018
Entry Details Article
Copy BDB DOIPubMed
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TargetTransient receptor potential cation channel subfamily V member 4(Rat)
Shionogi

Curated by ChEMBL

LigandBDBM50192817(CHEMBL3924485)Copy SMILESCopy InChI

Affinity DataIC50: 53nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/30/2018
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL