BDBM50193347 (Z)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)propan-1-one O-methyloxime::CHEMBL213486

SMILES CO\N=C(\CCN1CCN(CC1)c1ccccn1)c1ccccc1C

InChI Key InChIKey=RCSRPVRMQQOAEC-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193347   

TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193347((Z)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)pr...)
Affinity DataEC50:  40.1nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193347((Z)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)pr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193347((Z)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)pr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed