BDBM50193547 14beta-(2'-chlorocinnamoylamino)-7,8-dihydrocodeinone

SMILES COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(NC(=O)/C=C/c5ccccc5Cl)C(C2)N(C)CC[C@]314

InChI Key InChIKey=CEMNPQJBUQZWJA-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50193547   

TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193547BDBM50193547(14beta-(2'-chlorocinnamoylamino)-7,8-dihydrocodein...)
Affinity DataEC50:  0.5nMAssay Description:Stimulation of [35S]GTPgammaS binding to human recombinant MORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193547BDBM50193547(14beta-(2'-chlorocinnamoylamino)-7,8-dihydrocodein...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]Cl-DPDPE from human recombinant DOR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193547BDBM50193547(14beta-(2'-chlorocinnamoylamino)-7,8-dihydrocodein...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]DAMGO from human recombinant MOR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193547BDBM50193547(14beta-(2'-chlorocinnamoylamino)-7,8-dihydrocodein...)
Affinity DataEC50:  2.20nMAssay Description:Stimulation of [35S]GTP-gamma-S binding to human recombinant DORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193547BDBM50193547(14beta-(2'-chlorocinnamoylamino)-7,8-dihydrocodein...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]U-69593 from human recombinant KOR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193547BDBM50193547(14beta-(2'-chlorocinnamoylamino)-7,8-dihydrocodein...)
Affinity DataEC50:  8.5nMAssay Description:Stimulation of [35S]GTP-gamma-S binding to human recombinant KORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed