BDBM50194649 (2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide::CHEMBL378859

SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)N1CCC[C@@H]1C(=O)NCCC1CCNCC1

InChI Key InChIKey=KXGAHULLQRZYOM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50194649   

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194649((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194649((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]NMS binding to human cloned M4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194649((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  94nMAssay Description:Inhibition of [3H]NMS binding to human cloned M2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194649((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  260nMAssay Description:Inhibition of [3H]NMS binding to human cloned M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194649((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  950nMAssay Description:Inhibition of [3H]NMS binding to human cloned M5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed