BDBM50194995 6-((1H-imidazol-4-yl)methylamino)-4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinoline-3-carbonitrile::CHEMBL223877

SMILES N#Cc1cnc2cc(OCCCN3CCOCC3)c(NCc3cnc[nH]3)cc2c1Nc1ccc(F)c(Cl)c1

InChI Key InChIKey=FCBPMQZZBISZTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194995   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194995BDBM50194995(6-((1H-imidazol-4-yl)methylamino)-4-(3-chloro-4-fl...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of Tpl2 kinase by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed