BDBM50195000 6-((1H-pyrazol-3-yl)methylamino)-4-(3-chloro-4-fluorophenylamino)quinoline-3-carbonitrile::CHEMBL220233

SMILES N#Cc1cnc2ccc(NCc3ccn[nH]3)cc2c1Nc1ccc(F)c(Cl)c1

InChI Key InChIKey=CMLPPPWSDQLMBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195000   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195000BDBM50195000(6-((1H-pyrazol-3-yl)methylamino)-4-(3-chloro-4-flu...)
Affinity DataIC50: 74nMAssay Description:Inhibition of Tpl2 kinase by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed