BDBM50195134 (S)-N-(1,8-dioxo-1-(2-(2-phenyl-1H-indol-3-yl)ethylamino)nonan-2-yl)thiazole-5-carboxamide::CHEMBL217035

SMILES CC(=O)CCCCC[C@H](NC(=O)c1cncs1)C(=O)NCCc1c([nH]c2ccccc12)-c1ccccc1

InChI Key InChIKey=GXQSQZKYJSEKFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50195134   

TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195134((S)-N-(1,8-dioxo-1-(2-(2-phenyl-1H-indol-3-yl)ethy...)
Affinity DataIC50: 590nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195134((S)-N-(1,8-dioxo-1-(2-(2-phenyl-1H-indol-3-yl)ethy...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195134((S)-N-(1,8-dioxo-1-(2-(2-phenyl-1H-indol-3-yl)ethy...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC1 from human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed