BDBM50195499 (4-amino-3,5-dichlorophenyl)((2R,6S)-4-(2-methoxyphenyl)-2,6-dimethylpiperazin-1-yl)methanone::CHEMBL222576
SMILES COc1ccccc1N1C[C@H](C)N([C@H](C)C1)C(=O)c1cc(Cl)c(N)c(Cl)c1
InChI Key InChIKey=MCGVBZPHMZCELG-BETUJISGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50195499
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat 11beta-HSD2More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair