BDBM501957 US11028075, Example 90

SMILES OC1CCN(C1)[C@H]1C[C@H](CC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=NVUNPSBBEABLIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501957   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM501957(US11028075, Example 90)
Affinity DataIC50: 0.570nMAssay Description:The following voltage clamp electrophysiology studies are performed on representative compounds using cells heterologously expressing Nav1.7 or Nav1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent