BDBM50196587 CHEMBL253800::benzyl 1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-phenylbutan-2-ylamino)-3-(heptan-4-ylsulfonyl)-1-oxopropan-2-ylcarbamate

SMILES CCCC(CCC)S(=O)(=O)CC(NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1cccc(OC)c1

InChI Key InChIKey=FJYALDRNDKNYKU-DWJMSNRFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196587   

TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196587(CHEMBL253800 | benzyl 1-((2S,3R)-4-(3-methoxybenzy...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196587(CHEMBL253800 | benzyl 1-((2S,3R)-4-(3-methoxybenzy...)
Affinity DataIC50:  112nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed