BDBM50196763 CHEMBL3956031

SMILES CCOc1ccc(cc1-c1nc2c(CC)nn(C)c2c(=O)[nH]1)-c1ccc(nc1)C(=O)NO

InChI Key InChIKey=PLORDXSOTXFDIZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196763   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196763(CHEMBL3956031)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196763(CHEMBL3956031)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196763(CHEMBL3956031)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibition of full length recombinant human C-terminal His/Flag-tagged HDAC1 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196763(CHEMBL3956031)
Affinity DataIC50:  861nMAssay Description:Inhibition of full length recombinant human N-terminal GST tagged HDAC6 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed