BDBM50197067 CHEMBL3913746
SMILES CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccnc(Cl)c2)n1
InChI Key InChIKey=AWNXKZVIZARMME-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 30 hits for monomerid = 50197067
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human Vps34-Vps15 complex expressed in insect cells assessed as reduction in PtdIns phosphorylation incubated for 30 mins i...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human Vps34-Vps15 complex expressed in insect cells assessed as reduction in PtdIns phosphorylation in presence of gamma32P...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of VPS34 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human PIK3C3 using PI as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of human PIK3C3 using PI as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Guangzhou University of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 382nMAssay Description:Inhibition of PIP5K1C (unknown origin) using D-myo-PIP as substrate incubated for 45 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of PI4Kbeta (unknown origin) using D-myo-PtdIns as substrate incubated for 45 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PtdIns(4,5)P2 as substrate preincubated for 20 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PtdIns(4,5)P2 as substrate preincubated for 20 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of human PIP5K1C using PI/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of PI4Kalpha (unknown origin) using D-myo-PtdIns as substrate incubated for 45 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of human PIP5K1A using PI/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PtdIns(4,5)P2 as substrate preincubated for 20 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3CA/PIK3R1 using PIP2/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI4KB using PI as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Curtin University
Curated by ChEMBL
Curtin University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2beta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3C2A using PIP2/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2alpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3CG using PIP2/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3CD/PIK3R1 using PIP2/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3CB/PIK3R1 using PIP2/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI4K2B using PI/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3C2G using PIP2/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Curtin University
Curated by ChEMBL
Curtin University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3C2B using PIP2/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI4K2A using PI/PS as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Human)
Curtin University
Curated by ChEMBL
Curtin University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2gamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of PIP5K1A (unknown origin) using D-myo-PIP as substrate incubated for 45 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PtdIns(4,5)P2 as substrate preincubated for 20 mins followed by substrate addition and measured after 8...More data for this Ligand-Target Pair