BDBM50197513 (S)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden-2-yl)carbamoyl)cyclopentyl)methyl)-4-methoxybutanoic acid::CHEMBL225084

SMILES COCC[C@H](CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O

InChI Key InChIKey=GQXPQLZHUYKTKG-GOSISDBHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197513   

TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197513((S)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...)
Affinity DataIC50:  10nMpH: 7.4Assay Description:Inhibition of human kidney NEP at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197513((S)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...)
Affinity DataIC50:  3.70nMpH: 7.0Assay Description:Inhibition of human kidney NEP at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed