BDBM50197519 (S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid::CHEMBL224670

SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(F)cc1)C(O)=O

InChI Key InChIKey=MPWCDZKWKGSZCI-QGZVFWFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197519   

TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197519((S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyc...)
Affinity DataIC50:  4.60nMpH: 7.0Assay Description:Inhibition of human kidney NEP at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197519((S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyc...)
Affinity DataIC50:  12.6nMpH: 7.4Assay Description:Inhibition of human kidney NEP at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed