BDBM50197886 CHEMBL3936923

SMILES Cc1cccc(CNc2nc(nc(n2)N2CCNCC2)C#N)c1

InChI Key InChIKey=NJKWZQGOBIFPBG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197886   

TargetCathepsin S(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197886(CHEMBL3936923)
Affinity DataIC50: 17nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin K(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197886(CHEMBL3936923)
Affinity DataIC50: 23nMAssay Description:Inhibition of human cathepsin K expressed in Pichia pastoris using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin B(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197886(CHEMBL3936923)
Affinity DataIC50: 57nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed