BDBM50197887 CHEMBL3899928

SMILES O[C@@H](CNc1nc(nc(n1)N1CCNCC1)C#N)c1ccccc1

InChI Key InChIKey=TYRKGQFUSLPRSY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197887   

TargetCathepsin S(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197887(CHEMBL3899928)
Affinity DataIC50: 23nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197887(CHEMBL3899928)
Affinity DataIC50: 45nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin K(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197887(CHEMBL3899928)
Affinity DataIC50: 68nMAssay Description:Inhibition of human cathepsin K expressed in Pichia pastoris using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin B(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197887(CHEMBL3899928)
Affinity DataIC50: 136nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed