BDBM50197915 CHEMBL223815::N-(1-(3-chlorobenzyl)pyrrolidin-3-yl)isoquinolin-5-amine::N-[1-(3-chlorobenzyl)-3-pyrrolidyl]-N-(5-isoquinolyl)amine

SMILES Clc1cccc(CN2CCC(C2)Nc2cccc3cnccc23)c1

InChI Key InChIKey=UHJHCLYQRUAKGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197915   

TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50197915(CHEMBL223815 | N-(1-(3-chlorobenzyl)pyrrolidin-3-y...)
Affinity DataIC50:  65nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50197915(CHEMBL223815 | N-(1-(3-chlorobenzyl)pyrrolidin-3-y...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of MCP1-induced chemotaxis in U937 cells overexpressing CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed