BDBM50198019 22-[(1E)-3-(4,5-dihydro-1H-imidazol-2-ylamino)prop-1-en-1-yl]-16-(hydroxymethyl)-4,14,18-triazaheptacyclo[12.10.2.0^{2,6}.0^{7,26}.0^{8,13}.0^{18,25}.0^{19,24}]hexacosa-1(25),2(6),7(26),8,10,12,19(24),20,22-nonaen-3-one::CHEMBL388221

SMILES O=C1NCc2c1c1c3cc(/C=C/CN=C4NCCN4)ccc3n3c1c1c2c2ccccc2n1CC(CO)C3

InChI Key InChIKey=XEKQILODHWQBSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198019   

TargetTyrosine-protein kinase JAK3(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198019BDBM50198019(22-[(1E)-3-(4,5-dihydro-1H-imidazol-2-ylamino)prop...)
Affinity DataIC50: 31nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed