BDBM50198021 16-(hydroxymethyl)-22-[(E)-2-(pyridin-2-yl)ethenyl]-4,14,18-triazaheptacyclo[12.10.2.0^{2,6}.0^{7,26}.0^{8,13}.0^{18,25}.0^{19,24}]hexacosa-1(25),2(6),7(26),8,10,12,19(24),20,22-nonaen-3-one::CHEMBL243016

SMILES OCC1Cn2c3ccccc3c3c4CNC(=O)c4c4c5cc(\C=C\c6ccccn6)ccc5n(C1)c4c23

InChI Key InChIKey=BIJLGWWDWJZUPE-CSKARUKUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198021   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50198021(16-(hydroxymethyl)-22-[(E)-2-(pyridin-2-yl)ethenyl...)
Affinity DataIC50:  354nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed