BDBM50198495 (S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-5-(4-fluorophenyl)-N-methylpicolinamide::CHEMBL215660

SMILES CN(C)Cc1ccc2C[C@H](CCc2c1)N(C)C(=O)c1ccc(cn1)-c1ccc(F)cc1

InChI Key InChIKey=DHAIYNYURHDUCT-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198495   

TargetMelanin-concentrating hormone receptor 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198495((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataKi:  20nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198495((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198495((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed