BDBM50198504 (S)-4'-fluoro-N-methyl-N-(6-((3-oxopiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)biphenyl-4-carboxamide::CHEMBL214178

SMILES CN([C@H]1CCc2cc(CN3CCNC(=O)C3)ccc2C1)C(=O)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=ISKBVCXTQANZNE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198504   

TargetMelanin-concentrating hormone receptor 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198504((S)-4'-fluoro-N-methyl-N-(6-((3-oxopiperazin-1-yl)...)
Affinity DataKi:  145nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198504((S)-4'-fluoro-N-methyl-N-(6-((3-oxopiperazin-1-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed