BDBM50198942 (S)-1-butyl-3-((S)-1-hydroxy-2-methyl-propyl)-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride::CHEMBL558043

SMILES CCCCN1C(=O)[C@@H](NC(=O)C11CCN(Cc2ccc(Oc3ccccc3)cc2)CC1)[C@@H](O)C(C)C

InChI Key InChIKey=WUTCDIFLPLKLBC-UIOOFZCWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198942   

TargetC-C chemokine receptor type 5(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198942((S)-1-butyl-3-((S)-1-hydroxy-2-methyl-propyl)-9-(4...)
Affinity DataIC50:  53nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198942((S)-1-butyl-3-((S)-1-hydroxy-2-methyl-propyl)-9-(4...)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at human CCR5 expressed in CHO cells assessed as inhibition of MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed