BDBM50199675 CHEMBL239360::cis-1-(3-(benzyloxy)phenyl)-3-(3-((methyl(piperazin-1-yl)amino)methyl)cyclobutyl)-1,8a-dihydroimidazo[1,5-a]pyrazin-8-amine

SMILES CN(C[C@H]1C[C@H](C1)C1=NC(C2N1C=CN=C2N)c1cccc(OCc2ccccc2)c1)N1CCNCC1

InChI Key InChIKey=GUDFNEWEEHZYCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199675   

TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199675(cis-1-(3-(benzyloxy)phenyl)-3-(3-((methyl(piperazi...)
Affinity DataIC50: 758nMAssay Description:Inhibition of IGF1-stimulated phosphorylation of human recombinant IGF1R expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199675(cis-1-(3-(benzyloxy)phenyl)-3-(3-((methyl(piperazi...)
Affinity DataIC50: 758nMAssay Description:Inhibition of IGF1-stimulated phosphorylation of human recombinant IGF1R expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed