BDBM50199717 CHEMBL3909436

SMILES CCn1nc(cc(NC(=O)Nc2c(Cl)cncc2Cl)c1=O)-c1cccc(c1)-c1ccc(F)c(c1)C(O)=O

InChI Key InChIKey=PQDYQWWEDFXRQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199717   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50199717(CHEMBL3909436)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human recombinant PDE4B1 assessed as reduction in [3H]cAMP hydrolysis to [3H]AMP incubated for 60 mins by PDE-SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2018
Entry Details Article
PubMed