BDBM50199884 CHEMBL3953720

SMILES CC1CN(CCN1C(C)=O)c1ccc(Nc2ncc3ncn(-c4cccc(NC(=O)C=C)c4)c3n2)cc1

InChI Key InChIKey=BREVVBALZAVOPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199884   

TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50199884(CHEMBL3953720)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected sf9 cells using poly(4:1 Glu,Tyr) as substrate by ADP-Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50199884(CHEMBL3953720)
Affinity DataIC50: 61nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2018
Entry Details Article
PubMed