BDBM50200721 (R)-1-(2-(cyclohexanecarboxamido)acetyl)pyrrolidin-2-ylboronic acid::CHEMBL387444

SMILES OB(O)[C@@H]1CCCN1C(=O)CNC(=O)C1CCCCC1

InChI Key InChIKey=BDSCRXMWRYZJKF-NSHDSACASA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50200721   

TargetProlyl endopeptidase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50200721((R)-1-(2-(cyclohexanecarboxamido)acetyl)pyrrolidin...)
Affinity DataKi:  2.70nMAssay Description:Inhibitory constant against POPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl endopeptidase FAP(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50200721((R)-1-(2-(cyclohexanecarboxamido)acetyl)pyrrolidin...)
Affinity DataKi:  14nMAssay Description:Inhibitiory constant against FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl endopeptidase FAP(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50200721((R)-1-(2-(cyclohexanecarboxamido)acetyl)pyrrolidin...)
Affinity DataKi:  14nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDipeptidyl peptidase 4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50200721((R)-1-(2-(cyclohexanecarboxamido)acetyl)pyrrolidin...)
Affinity DataKi:  7.39E+3nMAssay Description:Inhibition constant against DPP-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDipeptidyl peptidase 4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50200721((R)-1-(2-(cyclohexanecarboxamido)acetyl)pyrrolidin...)
Affinity DataKi:  9.08E+3nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed