BDBM50200882 (R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL376414

SMILES CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C(C)(C)C)c(=O)c2=O)c1O

InChI Key InChIKey=MYFOCPUZNAPZSE-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50200882   

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200882BDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200882BDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200882BDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataKi:  14nMAssay Description:Displacement of Mz437 from CCR7 in live HEK293T cells expressing CCR7_GSSG_Nluc assessed as inhibition constant using furimazine as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200882BDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataKi:  36nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200882BDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataIC50: 1.28E+3nMAssay Description:Antagonist activity at human CCR7 expressed in HEK293T cells assessed as inhibition of CCL19 mediated Galpha-o activation using Nano-glo nanolucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed