BDBM50201291 CHEMBL394255::N,N-dimethyl-3-((2-(tetrahydropyran-4-ylidene)ethylamino)methyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine

SMILES [#6]-[#7](-[#6])C1([#6]-[#7]-[#6]\[#6]=[#6]-2\[#6]-[#6]-[#8]-[#6]-[#6]-2)[#6]-[#8]-c2ccccc2-[#8]-[#6]1

InChI Key InChIKey=RAIRSUZMFLTRDE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201291   

TargetMuscarinic acetylcholine receptor M2(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201291(N,N-dimethyl-3-((2-(tetrahydropyran-4-ylidene)ethy...)
Affinity DataKi:  8.80nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201291(N,N-dimethyl-3-((2-(tetrahydropyran-4-ylidene)ethy...)
Affinity DataKi:  14nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201291(N,N-dimethyl-3-((2-(tetrahydropyran-4-ylidene)ethy...)
Affinity DataKi:  86nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed